Solutions for Final Fill Processes

Parker can help you design and create customized single-use assemblies to meet the specific application needs of your process. With the flexibility to integrate the compontents of your choice, we can create single-use manifolds that fit your process, so you don't have to fit your process to a single-vendor's product. 

Our design, engineering and technical experts work closely with you from concept to reality to ensure a smooth introduction of the assembly into your process. 

To enable risk mitigation of storage and transport of the product prior to final fill, Parker's SciLog FD system can automate the down packing in a closed container system. The system can be configured to use either bags or bottles.   

Closed system bottle solutions with an open architecture enable efficient closed filling and draining processes. These solutions are perfectly suited for the freezing, low-temperature storage, and transportation of sensitive products while ensuring product integrity and safety.

To enable storage of process solutions, Parker can supply bioprocess containers manufactured using a high clarity, medical grade film that provide strength, flexibility, and a gas barrier as well as low extractables. The product contact layer of this five layer film is ultra low density polyethylene (ULDPE) and the gas barrier is ethylene vinyl alcohol (EVOH). 

Parker offers sampling solutions in a variety of materials and containers, including both bags and bottles for efficient collection, designed for efficient and closed sample collection.

Parker’s proprietory SciLog® Conductivity & Temperature Sensors arrive pre-calibrated and include a memory device that stores calibration data and sensor-specific information for traceability.

The monitoring and control of process conductivities and temperatures can increase the efficiency of downstream operations and provide critical in process data.

Monitors for use with SciLog® Single-Use Sensors are available for measurement with pressure, conductivity, or temperature.

In addition to displaying the outputs for its specific sensor type, each monitor will read and display the unique sensor serial number and factory calibration information recorded on each SciLog® Sensor’s memory chip.

When connected to a PC, real-time documentation of sensor data can be achieved.

The Parker SciLog®  range of intelligent pumps can help control your process flows by using data obtained from the sensors to automatically control the flow rate and safeguard your process.

The quality and safety of your final biopharmaceutical product depends on effective sterilizing grade filtration during critical bioprocessing applications. Parker’s validated sterilizing grade filters feature a 0.2 micron polyethersulfone (PES) membrane that combines high flow rates and low protein binding for efficient processing with minimal product loss. Filters are available in cartridge or capsule formats to meet the needs of your applications.

Parkers PUPSIT (Pre-Use and Post Sterilization Integrity Testing) filtration assemblies are designed for reliable sterile filtration to satisfy the requirements of the Annex 1 guidelines.

Parker’s proprietory SciLog® Pressure Sensors arrive pre-calibrated and include a memory device that stores calibration data and sensor-specific information for traceability.

Careful monitoring and control of pressure in critial applications such as final sterilizing filtration can ensure process conditions remain within validated limits. 

The SciLog® WeighStation Family is a range of mobile, single-use bioprocessing container holders with integrated scales for gravimetric fluid handling.

The Puretain Transfer Set integrates tubing into isolators facilitated by a flexible and secure molded port design. This overmolding solution is compatible with different tubing sizes, numbers, and brands which ensures sterile, leak-proof connections with beta bags or other beta transfer containers.

Final fill manifolds, featuring overmolding in pump tubing segments and available in various overmolded connections, are compatible with different tubing sizes, numbers, and brands. This closed system delivers flexible filling productivity, tailored to meet the manufacturing demands of manufacturing a range of drug products and fill volumes, while being flexible in design.