Achieving precision, safety and compliance in biopharmaceutical manufacturing requires reliable, high-performance solutions. From fluid management and filtration to sealing and single-use technologies, innovative process control systems help enhance product integrity, accelerate drug development and meet stringent industry standards. With cutting edge solutions designed for scalability and efficiency, manufacturers can optimise bioprocessing workflows while ensuring the highest levels of purity and performance.
Find out more about Parker's biopharma processing capabilities below.
Bioprocessing Applications
Cell Culture
Harvesting
Buffer Preparation
Purification and Concentration
Bulk Fill
Freezing
Final Fill
PUPSIT
Browse our Bioprocessing Technologies
Single-Use Solutions
Parker utilises the latest technologies and extensive engineering and process expertise to advance bioprocessing with our PureTain® single-use solutions.
Bioprocess Automation
The use of automation in running complex single use processes has many benefits including improving process control and consistency, increasing speed, and reducing human error deviations.
Filtration
From clarification and bioburden reduction to sterile filtration and Mycoplasma removal, Parker offers a range of liquid and gas filters for all your filtration requirements. Filters can be incorporated into our SciLog® single-use systems to enhance process control and increase productivity.
Single-Use Sensing
Parker’s single-use sensors for pressure, temperature and conductivity measurement enhance bioprocess control and safety making them fundamental for monitoring critical applications such as virus filtration, ultrafiltration and diafiltration and bulk drug dispense.
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Bioprocessing Solutions
Parker products and complete solutions for biopharmaceutical applications ensure high performance of the fluid control and filtration systems, maximising uptime and productivity. They are designed to meet the requirements of next generation Bioprocessing
Featured Products
SciLog NFF+ Automated NFF System with PUPSIT
Bioprocess Freezing Bottles, Puretain®
PROPOR MR Mycoplasma Removal Filters
PROPOR SG Sterilizing Grade Pharmaceutical Filters
PROPOR HC High Capacity Sterilizing Grade Filters
SciLog® FD Automated Filtration And Dispense System
Free Resources
Three Ways to Successfully Scale-Up
When developing a biopharmaceutical manufacturing process, an R&D or development team may fall into the trap of developing a process in the lab which is difficult to scale up for production volumes. Read how to avoid delays and additional development costs.
Application of Pre-Use Post Sterilisation Integrity Testing
The latest revision of EU GMP Annex 1: Manufacture of Sterile Medicinal Products (August 2023) included PUPSIT as a default requirement for manufacturers using filtration to sterilize their final product. Discover the considerations and challenges for the incorporation of PUPSIT into your processes.
Demystifying Extractables Testing
The increased focus by biomanufacturers on smaller patient populations is driving the adoption of technologies that can improve flexibility and process efficiency while also lowering overall costs. As a result, the application of single-use technology (SUT) is growing rapidly.
Improving Final Fill Processes and Addressing Annex 1 Requirements
Explore the evolving role of single-use systems in addressing critical challenges in final fill processes and meeting stringent regulatory requirements. Learn how Parker´s PureTain® solutions are reshaping processes, enhancing efficiency, and ensuring sterility, while aligning with regulatory standards.
Videos & Webinars
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Literature
Biopharmaceutical Industry Overview Guide
White Paper: Three ways to Successfully Scale-up
White Paper: Automation in Single-use
White Paper: Preventing Mycoplasma Contamination
White Paper: Demystifying Extractables Testing
White Paper: Implementation of Single-use
White Paper: Single-use-The next Five Challenges
About Parker's Pharmaceutical & Biopharma Solutions
At Parker, we provide a comprehensive range of biopharma solutions that enable biopharmaceutical manufacturers to ensure high performance, protected product, and compliance.
Parker's biopharma solutions feature a wide range of technologies designed to support the development and production of biopharmaceuticals.
With product safety, efficiency and compliance being key priorities for companies operating in the biopharma industry, Parker offers a wide range of solutions including single-use systems, bioprocess automation and contamination control technologies. Our range of biopharma solutions and products enable you to streamline the production process, minimise contamination risk and enhance overall efficiency.
Our complete solutions span the entire biopharma process. From upstream to downstream processing, powering every stage of biopharmaceutical production.
Our advanced solutions for upstream bioprocessing include products to support crucial steps during the upstream process, such as cell culture media prep and cell harvesting. Parker's PureTain® single-use solutions and SciLog® automation systems provide dependable, scalable, and effective solutions for processes supporting upstream bioprocessing e.g. cell culture media filtration via PROPOR MR filters validated to remove mycoplasma.
Preparing buffers is another critical step in the biopharmaceutical process. Our single-use fluid flowpaths simplify the buffer preparation process, using single-use materials and innovative filtration technology to ensure accuracy and reliability. Our single-use systems are designed to reduce contamination risks and improve workflow efficiency, ensuring accurate formulation. Some key products include the PureTain® single-use bottle mixing system and the PureTain® SpinBag mixing system.
In downstream processing purification and concentration take place to ensure the final product's quality and efficacy. During purification, impurities are removed using various techniques such as chromatography and filtration.
Our down stream processing solutions include a number of bioprocess automation solutions that allow you to optimise process efficiency in a flexible and scalable way. Leveraging automation solutions in the purification and concentration process with single-use assemblies has many benefits, such as reducing human error, increasing efficiency, and improving process control. Key products include SciLog® TFF Automated Tangential Flow Filtration Systems designed for tangential flow filtration applications such as diafiltration.
Post downstream processing but before final fill a bulk fill process is commonly used, here the drug is at its most valuable and at it’s highest volume, Parker's automated single-use solutions protect your product at this crucial stage. The SciLog® FD System automates the filtration and dispensing of bulk drug substance, enabling a safe and consistent process and providing an effective contamination control strategy, reducing the need for expensive environmental monitoring.
The biopharmaceutical freezing process enables product integrity to be preserved, especially for storage or cold chain transportation. Parker's PureTain® Freezing solutions ensure stability and sterility of the product are maintained until the final formulation process.
Key products to assist in the process include Parker’s PureTain® freezing bottles for freezing, transportation, and storage of drug substance or intermediates. Our customised solutions are designed to meet your needs and safeguard your biopharma product.
Our final fill solutions are designed to support regulatory requirements, such as EU GMP Annex 1. During the fill finish, the product is filled into vials or other primary packaging under sterile conditions. Sterile filling and filtration are critical processes, ensuring the final product is free from contamination and safety, ensuring the product is ready to be distributed and used.
As regulatory requirements continue to evolve in the biopharma industry. Guidelines such as EU GMP Annex 1 and EudraLex Annex 1, highlight PUPSIT as a default requirement for biopharmaceutical processing.
Parker offer full assemblies and easy-to-use PUPSIT filtration systems. These systems seamlessly integrate with your aseptic filling lines, whilst adhering to the latest regulatory requirements. These are available as manual, semi-automated or fully automated solutions and Parker’s innovative Y-piece technology (patent applied for) provides best in class filter wetting and integrity testing whether the process utilises a single or a redundant filtration set up.
Whether you are navigating laboratory scale up trials or enhancing your final fill process, Parker has a suite of bioprocessing applications and technologies enabling you to adhere to regulations and maintain integrity during the biopharmaceutical production process.
Get in touch with one of our biopharma experts to find the right biopharma solution for your processes.